A team of scientists from the Federal University of the Urals (Yekaterinburg), the Bangladesh University of Engineering and Technology and other collaborators published an article on a new method of synthesizing magnetic nanoparticles. Today, nanoparticles are used in a variety of fields, from biomedicine to magnetic resonance imaging, data storage systems, environmental recovery technologies, magnetically controlled liquids, various sensors, and monitoring systems. immunoassay.
Nanomaterial manufacturing is a popular field today, and like any other industry, it is meant to be environmentally friendly. Scientists are working on so-called green synthesis – environmentally friendly methods to produce nanomaterials from plant extracts. However, many substances contained in natural materials are unstable and quickly enter redox reactions with certain components of the environment. A stabilizer is a very important substance for the newly synthesized nanoparticles, which was one of the objectives of the study carried out by the team of scientists.
To synthesize iron oxide nanoparticles, the team used inorganic substances such as iron chloride and sodium hydroxide. Scientists also used an extract from the leaves of Ipomoea aquatica (a plant in the bindweed family) as a stabilizing and reducing agent. It helped prevent agglutination of the particles and supported their small size.
Besides the green nature of the process, the team paid attention to the different properties of the resulting nanoparticles. The ratio between the surface area of ââthe particle and its volume has played an important role in the reactivity of magnetic nanoparticles. All of this leads to adjusting the properties that are important for biology and medicine. They also studied the magnetic properties of nanoparticles stabilized with the extract of Ipomoea aquatica. To do this, they placed the particles in an external magnetic field at room temperature and monitored their behavior. The experiments showed some manifestations of the superparamagnetic nature of the particles. This is a particular form of magnetism that is specifically observed in ferromagnetic or ferrimagnetic particles of nanometric size.
According to several studies, it is established that the magnetic nature of nanoparticles improves the activity of drugs. The team also conducted an experiment to confirm that the new nanoparticles suppressed the growth of bacteria. Thus, the authors asserted that superparamagnetic nanoparticles at room temperature and their antibacterial properties would make them a potential material for biomedical applications.
âOur study of the different properties of the new nanoparticles confirmed that they meet all existing standards. The new methodology is based on plant raw materials and is therefore environmentally friendly, âsaid Hossain Aslam, research engineer at the Federal University of the Urals.
Magnetite (Fe3O4) (MNP) nanoparticles were synthesized by an easy green synthetic route using naturally available aqueous leaf extract of Ipomoea aquatica where the leaf extract biomolecules acted as a stabilizer as well as a reducing agent. The synthesized MNPs have a pronounced antibacterial activity against Gram-negative and Gram-positive bacteria. The superparamagnetic nature at room temperature and the antibacterial activity of MNPs demonstrate that they could be potential materials for biomedical applications.
Reference: “Ecological synthesis of Fe3O4 nanoparticles based on natural stabilizers and their antibacterial applications” by Mohammad M. Zaman, Dr Mohammad Abu S. Karal, Dr Mohammed Nazrul I. Khan, Abu Rayhan M. Tareq, Shareef Ahammed, Dr Mahmuda Akter , Aslam Hossain and AKM Atique Ullah, July 15, 2019, ChemistrySelect.
DOI: 10.1002 / slct.201901594
Illustration: Aslam Hossein